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Andrew Zydney | Curriculum Vitae


Education | lectures | Patents | Fellowships and Memberships
Lectures | All Publications

My current research activities are focused in three distinct areas: biomedical engineering, bioseparations, and membrane processes. In each of these areas, our goal is to develop a more fundamental understanding of the factors governing the behavior of these processes, including the complex interactions between the biological molecules/cells and the synthetic materials used in these devices.

Education

Doctorate - 1985 Massachusetts Institute of Technology
Bachelors - 1980 Yale University

Lectures

  • 2006, Recovery of Biological Products, ACS Meeting, Phoenix, AZ
  • 2006, FDA, Center for Drug Evaluation and Research, Visiting Lecturer, Bethesda, MD
  • 2006, Genentech, Inc., Recovery Sciences Seminar Series, San Francisco, CA
  • 2005, Millipore Corporation, Bioprocessing Division, Bedford, MA
  • 2005, 3M Corporation, St Paul, MN
  • 2005, City College of New York, Dept of Chemical Engineering, New York, NY
  • 2005, Amgen, Inc., Seattle, WA
  • 2005, Washington State University, Pullman, WA
  • 2005, International Congress on Membranes and Membrane Processes, Seoul, Korea
  • 2005, International Membrane Conference, Plenary Lecture, Chungli, Taiwan
  • 2005, Centocor, Distinguished Lecture Series, Malvern, PA
  • 2005, Drexel University, Dept of Chemical and Biological Engineering, Philadelphia, PA
  • 2005, U California at Santa Barbara, Dept of Chemical Engineering, Santa Barbara, CA
  • 2005, Georgia Tech, Department of Chemical Engineering, Atlanta, GA
  • 2004, University of Kentucky, Dept of Chem Eng and Materials Sci, Lexington, KY
  • 2004, Amersham Biosciences, AB, Uppsala, SWEDEN
  • 2004, North American Membrane Society, Bioseparations Keynote, Waikiki, HAWAII
  • 2004, Rensselaer Polytechnic Institute, Department of Chemical Eng, Troy, NY
  • 2004, 3M Corporation, St. Paul, MN
  • 2003, University of Virginia, Department of Chemical Engineering, Charlottesville, VA
  • 2003, Genentech, Inc., Seminar Series, San Francisco, CA
  • 2003, Millipore Corporation, Bedford, MA
  • 2003, Recovery of Biological Products Meeting, Banff, Canada
  • 2003, Merck & Co., Danville, PA
  • 2003, Pennsylvania State University, Bioengineering Department, State College, PA
  • 2003, Genentech, Inc., Recovery Sciences Seminar Series, San Franciso, CA
  • 2002, Materials Research Society Meeting, Keynote Lecture, Boston, MA
  • 2002, Dow Chemical Company, Midland, MI
  • 2002, Conference on Undergraduate Research and Scholarship, College Park, MD
  • 2002, American Electrophoresis Society, Plenary Lecture, Indianapolis, IN
  • 2002, Cabot Corporation, Technology Innovation Workshop, Cambridge, MA
  • 2002, University of Delaware, College of Engineering, Order of the Ring, Newark, DE
  • 2002, Merck & Co., Inc., Natural Products Separations, Rahway, NJ
  • 2002, Merck & Co., Inc., Merck Research Laboratories, West Point, PA
  • 2001, University of Colorado, Chemical Engineering, Boulder, CO
  • 2001, Engineering Foundation Conf on Advanced Membrane Technol, Barga, Italy
  • 2001, Biogen Corporation, Cambridge, MA
  • 2004, Outstanding Professor Award, AIChE Chapter, Penn State
  • 1999, Distinguished Teacher Award, Mid-Atlantic Section of the American Society for Engineering Education
  • 1998, Fellow, American Institute for Medical and Biological Engineering
  • 1994, Excellence in Teaching Award, University of Delaware, Awarded to only 4 out of more than 1000 faculty at the University of Delaware for excellence in teaching.
  • 1990, Dow Outstanding Young Faculty Award, Mid Atlantic Section of the American Society for Engineering Education
  • 1990, Special Faculty Award, College of Engineering, University of Delaware, Awarded for outstanding contributions in education in the College of Engineering
  • 1986, International Bioengineering Prize, Kolff 75 International Symposium on Biomedical Engineering, Artificial Organs an, Awarded for the Best Bioengineering Thesis for 1982-1985. Included cash award of $10,000.
  • 1986, Outstanding Faculty Award, Mortar Board of Delaware, Awarded to one faculty member in each college in recognition of outstanding teaching.
  • 1985, Shell Faculty Fellow, University of Delaware
  • 1983, Whitaker Health Sciences Fund Fellowship, Whitaker Health Sciences Fund, Competitive fellowship in biomedical engineering for two years of graduate study.
  • 1980, National Science Foundation Graduate Fellowship, National Science Foundation, National competitive fellowship for three years of graduate study.
  • 1980, Honor Society, Phi Beta Kappa
  • 1980, Honor Society, Sigma Xi
  • 1980, Honor Society, Tau Beta Pi

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Patents

Fellowships and Memberships

  • American Chemical Society
  • American Institute for Medical and Biological Engineers
  • American Institute of Chemical Engineers
  • American Society for Engineering Education
  • American Water Works Association
  • Juvenile Diabetes Foundation, International
  • North American Membrane Society - Chair, Membership Committee
  • OccuLogix Corporation - Scientific and Medical Advisory Board
  • Separation Science and Technology - Associate Editor
  • Journal of Membrane Science - Editorial Board
  • Separation and Purification Methods - Editorial Board
  • International Congress on Membranes and Membrane Processes, Toulouse, France - Scientific Organizing Committee
  • European Society of Membrane Science and Technology, Germany - Scientific Organizing Committee
  • Separations Division of the American Institute of Chemical Engineers - Chair, Membrane-Based Separations Area
  • Engineering Foundation Conference on Advanced Membrane Technology, Barga Italy - Scientific Organizing Committee
  • American Society for Artificial Internal Organs - Program Committee

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Lectures

  • 2001, Glaxo-SmithKline, King of Prussia, PA
  • 2001, Pennsylvania State University, Chemical Engineering, State College, PA
  • 2001, Mykrolis Corporation, Bedford, MA
  • 2000, Merck Research Laboratories, Merck & Co., Inc., West Point, PA
  • 2000, American Chemical Society, Delaware Section, Wilmington, DE
  • 2000, Genetics Institute, Andover, MA
  • 2000, Millipore Corporation, Bedford, MA
  • 2000, Biogen Corporation, Cambridge, MA
  • 2000, Separation & Purification, Gordon Research Conference, New London, NH
  • 2000, Merck & Co., Inc., Bioprocess Division, Rahway, NJ
  • 2000, 3rd China-U.S. Chemical Engineering Conference, Beijing, China
  • 2000, Cepheid Incorporated, Sunnyvale, CA
  • 1999, NIH Biology/Chemistry Interface Program, Newark, DE
  • 1999, American Filtration Society, Plenary Lecture, Boston, MA
  • 1999, International Biotechnology Conference, BioTheapeutics '99, Washington, DC
  • 1999, Honorary Session for Alan Michaels, AIChE Meeting, Dallas, TX
  • 1998, Shaping the Future Conference, Manhattan, KA
  • 1998, E.I. DuPont de Nemours & Co., Bioprocessing Seminar Series, Wilmington, DE
  • 1998, Merck & Co., Inc., West Point, PA
  • 1998, European Dairy Symposium, NIZO 50, NETHERLANDS
  • 1998, University of Twente, Center of Membrane Science, NETHERLANDS
  • 1998, Yale University, Department of Chemical Engineering, New Haven, CT
  • 1998, Delaware AIChE Chapter, Local Meeting, Wilmington, DE
  • 1997, Membrane Technology Conference Workshop, AWWA, New Orleans, LA
  • 1997, Merck & Co., Inc., West Point, PA
  • 1997, Gordon Research Conference on Membranes, Andover, NH
  • 1997, Academy of Lifelong Learning, Wilmington, DE
  • 1997, Wyeth Lederle Vaccines and Pediatrics, Sanford, NC
  • 1996, Technical University of Copenhagen, Chemical Engineering, DENMARK
  • 1996, Baxter Healthcare Corporation, Renal Division, McGaw Park, IL
  • 1996, American Society for Artificial Internal Organs, Annual Meeting, Washington, DC
  • 1996, Workshop on Colloid Science in Membrane Engineering, Toulouse, FRANCE
  • 1996, Rutgers University, Department of Chemical and Biochemical Eng, Piscataway, NJ
  • 1996, Genetics Institute, Andover, MA
  • 1995, International Conference on Biofunctional Membranes, Lexington, KY
  • 1995, University of Cincinnati, Dept. of Chemical Engineering, Cincinnati, OH
  • 1995, University of Delaware, Chemistry - Biology Interface Program, Newark, DE
  • 1995, The Johns Hopkins University, Dept. of Chemical Engineering, Baltimore, MD
  • 1995, E.I. DuPont de Nemours & Co., UD/DuPont Symposium, Wilmington, DE
  • 1994, Genetech, Inc., Engineering Technology Seminar Series, San Francisco, CA
  • 1994, Pharmacia, BioProcess Technology, SWEDEN
  • 1994, Lappeenranta University of Technology, Dept of Chemical Tech, FINLAND
  • 1994, indhoven University of Technology, Dept of Chemical Eng, NETHERLANDS
  • 1994, Akzo Research Laboratories, Arnhem, NETHERLANDS
  • 1994, University of Twente, Center of Membrane Science, NETHERLANDS
  • 1994, Genentech, Inc., Engineering Technology Seminar Series, San Francisco, CA
  • 1994, Baxter Healthcare Corporation, McGaw Park, IL
  • 1994, Engineering Foundation Conf on Recovery of Biological Products, San Diego, CA
  • 1994, University of Colorado, Dept. of Chemical Engineering, Boulder, CO
  • 1994, SmithKline Beecham Pharmaceuticals, King of Prussia, PA
  • 1993, DNX Corporation, Princeton, NJ
  • 1993, University of Delaware, Dept. of Chemistry, Newark, DE
  • 1993, University of Kentucky, Center of Membrane Sciences, Lexington, KY
  • 1993, Cytotherapeutics Inc., Providence, RI
  • 1993, W. R. Grace & Co., Washington Research Center, Columbia, MD
  • 1992, University of Colorado at Boulder, Department of Chemical Eng, Boulder, CO
  • 1992, University of Maryland, Baltimore County Campus, Baltimore, MD
  • 1992, Merck Pharmaceutical Manufacturing Division, West Point, PA
  • 1992, Engineering Foundation Conf on Recovery of Biological Products, Interlaken, SWITZ
  • 1992, Membrane Technology/Separations Planning Conference, Boston, MA
  • 1992, Cornell University, School of Chemical Engineering, Ithaca, NY
  • 1991, University of Notre Dame, Department of Chemical Engineering, Notre Dame, IN
  • 1991, University of Iowa, Department of Chemical and Biochemical Eng, Iowa City, IA
  • 1991, SmithKline Beecham, King of Prussia, PA
  • 1991, Baxter Healthcare Corporation, RoundLake, IL
  • 1991, Second US/Germany Workshop on Downstream Processing, GERMANY
  • 1990, Engineering Foundation Conf on the Recovery of Biol Products, St. Petersburg, FL
  • 1990, Baxter Healthcare Corporation, RoundLake, IL
  • 1990, Gordon Research Conference on Synthetic Membranes, Plymouth, NH
  • 1990, Sepracor, Inc., Marlborough, MA
  • 1990, Rensselaer Polytechnic Institute, Department of Chemical Eng, Troy, NY
  • 1989, W. R. Grace and Co., Washington Research Center, Columbia, MD
  • 1989, Rutgers University, Department of Chemical and Biochemical Eng, Piscataway, NJ
  • 1989, University of Delaware Biotechnology Seminar Series, Newark, DE
  • 1989, Amicon Corporation, Division of W.R. Grace and Co., Lexington, MA
  • 1989, Baxter Healthcare Corporation, RoundLake, IL
  • 1989, University of Pennsylvania, Department of Chemical Engineering, Philadelphia, PA
  • 1988, Juvenile Diabetes Foundation, Delaware Chapter, Wilmington, DE
  • 1988, E. I. du Pont de Nemours and Co., Experimental Station, Wilmington, DE
  • 1988, World Congress on Medical Physics and Biomedical Engineering, San Antonio, TX
  • 1988, E. I. du Pont de Nemours and Co., Separations Panel Seminar, Wilmington, DE
  • 1987, University of Delaware Research Foundation, Newark, DE
  • 1986, Baxter Healthcare Corporation, RoundLake, IL
  • 1985, BioExpo 85, Biotechnology Symposium, Boston, MA
  • 1984, Millipore Corporation, Bedford, MA

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All Publications

  1. Zydney, A. L., and C. K. Colton, "Continuous Flow Membrane Plasmapheresis: Theoretical Models for Flux and Hemolysis Prediction", Trans. Am. Soc. Artif. Intern. Organs, 28, 408-412 (1982)

  2. Zydney, A. L., and C. K. Colton, "Mass Transport in Membrane Plasmapheresis", Proc. Third Int. Conf. Mech. Med. Biol., Compiegne, France, 1982

  3. Zydney, A. L., and C. K. Colton, "A Red Cell Deformation Model for Hemolysis in Cross Flow Membrane Plasmapheresis", Chem. Eng. Commun., 30, 191-207 (1984)

  4. Zydney, A. L., and C. K. Colton, "A Concentration Polarization Model for Filtrate Flux in Cross-Flow Microfiltration of Particulate Suspensions", Chem. Eng.Commun., 47, 1-21 (1986)

  5. Zydney, A. L., and C. K. Colton, "Fundamental Studies and Design Analyses of Cross-Flow Membrane Plasmapheresis", Artificial Organs, 343-358 (1987)

  6. Robertson, B. R., and A. L. Zydney, "Polarization and Adsorption Effects on Sieving in Membrane Protein Filtration", Trans. Am. Soc. Artif. Intern. Organs, 33, 118-122 (1987)

  7. Zydney, A. L., and C. K. Colton, "Augmented Solute Transport in the Shear Flow of a Concentrated Suspension", Physicochem. Hydrodynamics, 10, 77-96 (1988)

  8. Pillarella, M. R., and A. L. Zydney, "Solute Transport in a Hybrid Bioartificial Pancreas", Physics in Medicine and Biology, 33 (supplement 1), 237 (1988)

  9. Fox, C. F., M. Bier, D. Bruley, W. N. Drohan, J. Dwyer, J. Hord, R. Jordan, W. S. Kelley, B. Landis, R. Lovrien, B. McCoy, D. D. Y. Ryu, W. Velander, and A. L. Zydney, "Technologies for Purifying Blood Proteins with Therapeutic Applications: Current Status, Future Needs", Report from UCLA Symposia, National Research Priority Assessment Workshop (1988)

  10. Pillarella, M. R., and A. L. Zydney, "Analysis of Solute Clearance and Flux in Pre- and Post-dilution Hemofiltration", Trans. Am. Soc. Artif. Intern. Organs, 34, 415-419 (1988)

  11. Robertson, B. C., and A. L. Zydney, "Stefan-Maxwell Diffusion Analysis of Selective Protein Transport in Porous Membranes", Sep. Sci. Tech., 23, 1799-1811 (1988)

  12. Zydney, A. L., W. M. Saltzman, and C. K. Colton, "Hydraulic Resistance of Red Cell Beds in an Unstirred Filtration Cell", Chem. Eng. Sci., 44, 147-159 (1989)

  13. Buzdygon, K. J., and A. L. Zydney, "Effect of Storage Time on Red Cell Membrane Permeability to Creatinine and Uric Acid", Trans. Am. Soc. Artif. Intern. Organs, 35, 693-696 (1989)

  14. Kelsey, L. J., M. R. Pillarella, and A. L. Zydney, "Theoretical Analysis of Convective Flow in Hollow Fiber Membrane Bioreactors", Chem. Eng. Sci., 45, 3211-3220 (1990)

  15. Opong, W. S., and A. L. Zydney, "Effect of Protein Deposition on Hydraulic Permeability of Ultrafiltration and Microfiltration Membranes", Proceedings of the International Congress on Membranes and Membrane Technol, Vol I, 622-624 (1990)

  16. Pillarella, M. R., and A. L. Zydney, "Theoretical Analysis of the Effect of Convective Flow on Solute Transport and Insulin Release in a Hollow Fiber Bioartificial Pancreas", J. Biomech. Eng., 112, 220-228 (1990)

  17. Kelsey, L. J., and A. L. Zydney, "Fluid Flow in Hollow Fiber Membrane Bioreactors", Proceedings of the International Congress on Membranes and Membrane Technol, Vol II, 939-941 (1990)

  18. Mochizuki, S., A. L. Zydney, and W. S. Opong, "Macromolecular Sieving by Protein Deposits Formed During Ultrafiltration and Microfiltration", Proceedings of the International Congress on Membranes and Membrane Technol, Vol II, 1137-1139 (1990)

  19. Pillarella, M. R., and A. L. Zydney, "Effect of Beta Cell Distribution on the Performance of a Bioartificial Pancreas", Trans. Am. Soc. Artif. Intern. Organs, 36, M715-M719 (1990)

  20. Robertson, B. C., and A. L. Zydney, "Hindered Protein Diffusion in Asymmetric Ultrafiltration Membranes with Highly Constricted Pores", J. Membrane Sci., 49, 287-303 (1990)

  21. Robertson, B. C., and A. L. Zydney, "Protein Adsorption in Asymmetric Ultrafiltration Membranes with Highly Constricted Pores", J. Colloid Interface Sci., 134, 563-575 (1990)

  22. Opong, W. S., and A. L. Zydney, "Hydraulic Permeability of Protein Layers Deposited During Ultrafiltration", J. Colloid Interface Sci., 142, 41-60 (1991)

  23. Langsdorf, L. J., and A. L. Zydney, "Red Blood Cell Membrane Permeability for Normal and Uremic Cells", Trans. Am. Soc. Artif. Intern. Organs, 37, M461-M462 (1991)

  24. Zydney, A. L., J. D. Oliver, and C. K. Colton, "A Constitutive Equation for the Viscosity of Stored Red Blood Cell Suspensions: Effect of Hematocrit, Shear Rate, and Suspending Phase", J. Rheology, 35, 1639-1680 (1991)

  25. Opong, W. S., and A. L. Zydney, "Diffusive and Convective Protein Transport Through Asymmetric Membranes", AIChE J., 37, 1497-1510 (1991)

  26. Mochizuki, S., and A. L. Zydney, "Dextran Transport Through Asymmetric Ultrafiltration Membranes: Comparison with Hydrodynamic Models", J. Membrane Sci., 68, 21-41 (1992)

  27. Opong, W. S., and A. L. Zydney, "Effect of Membrane Structure and Solute Concentration on the Osmotic Reflection Coefficient", J. Membrane Sci., 72, 277-292 (1992)

  28. Mochizuki, S., and A.L. Zydney, "Effect of Protein Adsorption on the Transport Characteristics of Asymmetric Ultrafiltration Membranes", Biotechnology Progress, 8, 553-561 (1992)

  29. Saksena, S., and A. L. Zydney, "Protein Adsorption and Bulk Mass Transfer Effects in Selective Membrane Filtration", Proceedings, American Institute of Chemical Engineers Conference, 816-821 (1992)

  30. Zydney, A. L., "Concentration Effects on Membrane Sieving: Development of a Stagnant Film Model Incorporating the Effects of Solute-Solute Interactions", J. Membrane Sci., 68, 183-190 (1992)

  31. Mochizuki, S., and A. L. Zydney, "Theoretical Analysis of the Effects of a Pore Size Distribution on Membrane Transport", Proceedings of the International Congress on Membranes and Membrane Process (1993)

  32. Palecek, S. P., S. Mochizuki, and A. L. Zydney, "Effect of Ionic Environment on BSA Filtration and the Properties of BSA Deposits", Desalination, 90, 147-160 (1993)

  33. Mochizuki, S., and A.L. Zydney, "Sieving Characteristics of Albumin Deposits Formed During Microfiltration", J. Colloid Interface Sci., 158, 136-145 (1993)

  34. Langsdorf, L. J., and A. L. Zydney, "Effect of Uremia on the Membrane Transport Characteristics of Red Blood Cells", Blood, 81, 820-827 (1993)

  35. Kelly, S. T., W. S. Opong, and A. L. Zydney, "The Influence of Protein Aggregates on the Fouling of Microfiltration Membranes During Stirred Cell Filtration", J. Membrane Sci., 80, 175-187 (1993)

  36. McGettigan, K. L., S. T. Kelly, and A. L. Zydney, "Comparison of Protein Fouling in Stirred Cell and Cross-Flow Filtration Devices", Advances in Filtration and Separation Technology, 7, 431-434 (1993)

  37. Zydney, A. L., "Bulk Mass Transport Limitations During High-Flux Hemodialysis,", Artif. Organs, 17, 919-924 (1993)

  38. Langsdorf, L. J., Krankel, L. G., and A. L. Zydney, "Effect of Blood-Membrane Interactions on Middle Molecule Clearance During Hemodialysis", Trans. Am. Soc. Artif. Intern. Organs, 39, M767-M772 (1993)

  39. Mochizuki, S., and A. L. Zydney, "Theoretical Analysis of Pore Size Distribution Effects on Membrane Transport", J. Membrane Sci., 82, 211-228 (1993)

  40. Pujar, N. S., S. Saksena, and A. L. Zydney, "Electrostatic Interactions in Protein Transport Through Asymmetric Ultrafiltration Membranes", Proceedings of the International Congress on Membranes and Membrane Process, 1993

  41. Soltys, P. J., N. J. Ofsthun, and A. L. Zydney, "Theoretical and Experimental Studies of the Anisotropic Sieving Characteristics of Dual-Skinned Membranes", Proceedings of the International Congress on Membranes and Membrane Process, 1993

  42. Langsdorf, L. J., and A. L. Zydney, "Effect of Blood-Membrane Interactions on the Transport Characteristics of Hemodialysis Membranes", Blood Purification, 12, 292-307 (1994)

  43. Boyd, R. F., L. J. Langsdorf, and A. L. Zydney, "A Two-Layer Model for the Effects of Blood Contact on Membrane Transport in Artificial Organs", Trans. Am. Soc. Artif. Intern. Organs, 40, M864-M869 (1994)

  44. Saksena, S., and A. L. Zydney, "Effect of Solution pH and Ionic Strength on the Separation of Albumin from Immunoglobulins (IgG) by Selective Membrane Filtration", Biotech. Bioeng., 43, 960-968 (1994)

  45. Pujar, N. S., and A. L. Zydney, "Electrostatic and Electrokinetic Interactions During Protein Transport Through Narrow Pore Membranes", Ind. Eng. Chem. Res., 33, 2473-2482 (1994)

  46. Langsdorf, L. J., and A. L. Zydney, "Diffusive and Convective Transport through Hemodialysis Membranes: Comparison with Hydrodynamic Predictions", J. Biomed. Materials Res., 28, 573-582 (1994)

  47. Palecek, S. P., and A. L. Zydney, "Intermolecular Electrostatic Interactions and their Effect on Flux and Protein Deposition During Protein Filtration", Biotech. Prog., 10, 207-213 (1994)

  48. Kelsey-Tracey, L.J., L. J. Langsdorf, and A. L. Zydney, "Solute Diffusion through Porous Membranes and Its Application to Membrane Bioreactors", Bioseparation, 4, 165-174 (1994)

  49. Langsdorf, L. J., and A. L. Zydney, "Effect of Solution Environment on the Permeability of Red Blood Cells", Biotech. Bioeng., 43, 115-121 (1994)

  50. Ofsthun, N. J., and A. L. Zydney, "The Importance of Convection in Artificial Kidney Treatment," in Effective Hemodiafiltration: New Methods, edited by K. Maeda and T. Shinzato (1994)

  51. Kelly, S. T., and A. L. Zydney, "Effect of Intermolecular Thiol-Disulfide Interchange Reactions on BSA Fouling During Microfiltration", Biotech. Bioeng., 44, 972-982 (1994)

  52. Palecek, S. P., and A. L. Zydney, "Hydraulic Permeability of Protein Deposits Formed During Microfiltration: Effect of Solution pH and Ionic Strength", J. Membrane Sci., 95, 71-82 (1994)

  53. Belfort, G., R. H. Davis, and A. L. Zydney, "The Behavior of Suspensions and Macromolecular Solutions in Crossflow Microfiltration", J. Membrane Sci., 96, 1-58 (1994)

  54. Zydney, A. L., P. Aimar, M. Meireles, J. M. Pimbley, and G. Belfort, "Use of the Log-Normal Probability Density Function to Analyze Membrane Pore Size Distributions: Functional Forms and Discrepancies", J. Membrane Sci., 91, 293-298 (1994)

  55. Zydney, A. L., "Therapeutic Apheresis and blood Fractionation," in The Biomedical Engineering Handbook, edited by J. D. Bronzino, CRC Press and IEC Press, pp. 1936 - 1951, (1995)

  56. Zydney, A. L., "Boundary Effects on the Electrophoretic Motion of a Charged Sphere in a Concentric Spherical Pore", J. Colloid Interface Sci., 169, 476-485 (1995)

  57. Eijndhoven, H.C.M., S. Saksena, and A. L. Zydney, "Comparison of Batch and Diafiltration Processes for Protein Fractionation Using Semi-Permeable Membranes", Proceedings of Euromembrane 95, II, 366-369 (1995)

  58. Saksena, S., and A. L. Zydney, "Pore Size Distribution Effects on Electrokinetic Phenomena in Semipermeable Membranes", J. Membrane Sci., 105, 203-216 (1995)

  59. Zydney, A. L., "A Conceptual Design Problem in Mass Transfer Operations", Chem. Eng. Education, 29, 182-186 (1995)

  60. Kelly, S. T., and A. L. Zydney, "Mechanisms for BSA Fouling During Microfiltration", J. Membrane Sci., 107, 115-127 (1995)

  61. van Eijndhoven, H.C.M., S. Saksena, and A. L. Zydney, "Protein Fractionation Using Membrane Filtration: Role of Electrostatic Interactions", Biotech. Bioeng., 48, 406-414 (1995)

  62. Zydney, A.L., "Non-Specific Protein-Membrane Interactions: Adsorption and Fouling", Biofunctional Membranes, 279-288 (1996)

  63. Boyd, R. F., L. Y. Santiago, G. Lopez, C. L. Stephens, G. M. Velez, A. L. Zydney, and C. A. Ramirez, "Solute transport in the hybrid artificial pancreas device: In vitro results and mathematical simulation", Proceedings of the World Congress on Chemical Engineering, 785-791 (1996)

  64. Pujar, N. S., and A. L. Zydney, "Boundary Effects on the Sedimentation and Hindered Diffusion of Charged Particles", AIChE J., 42, 2101-2111 (1996)

  65. Soltys, P. S., N. J. Oftshun, and A. L. Zydney, "Asymmetric Solute Transport and Solvent Flux in Dual-Skinned Hollow Fiber Membranes", J. Membrane Sci., 118, 199-212 (1996)

  66. Menonparambil, M., D. B. Burns, and A. L. Zydney, "Effect of Protein Charge on Membrane Transport: Use of Capillary Electrophoresis to Correlate Sieving Data", Proceedings of the American Chemical Society Meeting, (1997)

  67. Saksena, S., and A. L. Zydney, "Influence of Protein-Protein Interactions on Bulk Mass Transport in Ultrafiltration", J. Membrane Sci., 125, 93-108 (1997)

  68. Kelly, S.T., and A.L. Zydney, "Protein Fouling During Microfiltration: Comparative Behavior of Different Model Proteins", Biotech. Bioeng., 55, 91-100 (1997)

  69. van Reis, R., E. M. Goodrich, C. L. Yson, L. N. Frautschy, R. Whiteley, and A. L. Zydney, "Constant Cwall Ultrafiltration Process Control", J. Membrane Sci., 130, 123-140 (1997)

  70. Zydney, A.L., "Stagnant Film Model for Concentration Polarization in Membrane Systems", J. Membrane Sci., 23, 275-282 (1997)

  71. van Reis, R., S. Gadam, L. N. Frautschy, S. Orlando, E. M. Goodrich, S. Saksena, R. Kuriyel, C. M. Simpson, S. Pearl, and A. L. Zydney, "High Performance Tangential Flow Filtration", Biotech. Bioeng., 56, 71-82 (1997)

  72. Boyd, R. F., and A. L. Zydney, "Transport Characteristics of Multilayer Ultrafiltration Membranes", J. Membrane Sci., 131, 155-166 (1997)

  73. Pujar, N.S., and A. L. Zydney, "Charge Regulation and Electrostatic Interactions for a Spherical Particle in a Cylindrical Pore", J. Colloid Interface Sci., 192, 338- 349 (1997)

  74. Velez, G. M., C. L. Stephens, L. Y. Santiago, G. Lopez, R. F. Boyd, and A. L. Zydney, "Mass Transfer in Hollow Fiber-Type Artificial Pancreas Devices", Fed. Amer. Soc. Exp. Biol., 11, 1676 (1997)

  75. Gadam, S., M. Phillips, S. Orlando, R. Kuriyel, S. Pearl, and A. Zydney, "A Liquid Porosimetry Technique for Correlating Intrinsic Sieving: Applications for Ultrafiltration Processes", J. Membrane Sci., 133, 111- 125 (1997)

  76. Menon, M.K., and A. L. Zydney, "Measurement of Protein Charge and Ion Binding Using Capillary Electrophoresis", Analytical Chemistry, 70, 1581-1584 (1998)

  77. Chapman Wilbert, M., J. Pellegrino, and A. L. Zydney, "Bench-Scale Testing of Surfactant Modified Reverse Osmosis/Nanofiltration Membranes", Desalination, 115, 15-32 (1998)

  78. Zydney, A.L., and N.S. Pujar, "Protein Transport Through Porous Membranes: Effect of Colloidal Interactions", Colloids Surfaces. A: Physicochem. Eng. Aspects, 138, 133-143 (1998)

  79. Boyd, R. F., and A. L. Zydney, "Analysis of Protein Fouling During Ultrafiltration Using a Two-Layer Membrane Model", Biotech. Bioeng., 59, 451-460 (1998)

  80. Pujar, N.S., and A. L. Zydney, "Electrostatic Effects on Protein Partitioning in Size Exclusion Chromatography and Membrane Ultrafiltration", J. Chromatography A, 796, 229-238 (1998)

  81. Boyd, R.F., M. Lopez, C. L. Stephens, G. M. Velez, L. Y. Santiago, C. A. Ramirez, and A. L. Zydney, "Solute Washout Experiments for Characterizing Mass Transport in Hollow Fiber Immunoisolation Membranes", Annals Biomed. Eng., 26, 618-626 (1998)

  82. Belfort, G., and A. L. Zydney, "Interaction of Proteins with Polymeric Synthetic Membranes," in Biopolymers at Interfaces, edited by M. Malmsten, pp. 513-559, Marcel Dekker, Inc., New York (1998)

  83. Morti, S.M., and A. L. Zydney, "Protein-Membrane Interactions During Hemodialysis: Effects on Solute Transport", Amer. Soc. Artif. Intern. Organs J., 44, 319-326 (1998)

  84. Zydney, A. L., "Protein Separations Using Membrane Filtration: New Opportunities for Whey Fractionation", International Dairy J., 8, 243-250 (1998)

  85. van Reis, R., and A. L. Zydney, "Protein Ultrafiltration," in Encyclopedia of Bioprocess Technology: Fermentation, Biocatalysis, and Bioseparation, edited by M.C. Flickinger and S.W. Drew, pp. 2197-2214, John Wiley & Sons, Inc. (1999)

  86. Yuan, W., and A. L. Zydney, "Humic Acid Fouling During Microfiltration", J. Membrane Sci., 157, 1-12 (1999)

  87. Zydney, A. L., in Advances in Filtration and Separation Technology, (1999)

  88. Ho, C-C., and A. L. Zydney, "Theoretical Analysis of the Effect of Membrane Morphology on Fouling During Microfiltration", Sep. Sci. Tech., 34, 2461-2483 (1999)

  89. Yuan, W., and A. L. Zydney, "Effect of Solution Conditions on Humic Acid Fouling During Microfiltration", Desalination, 122, 63-76 (1999)

  90. Ho, C-C., and A. L. Zydney, "Effect of Membrane Morphology on Protein Fouling During Microfiltration", J. Membrane Sci., 155, 261- 276 (1999)

  91. van Reis, R., J. M. Brake, J. Charkoudian, D. B. Burns, and A. L. Zydney, "High Performance Tangential Flow Filtration Using Charged Membranes", J. Membrane Sci., 159, 133- 142 (1999)

  92. Burns, D. B., and A. L. Zydney, "Effect of Solution pH on Protein Transport Through Semipermeable Ultrafiltration Membranes", Biotech. Bioeng., 64, 27-37 (1999)

  93. Menon, M. K., and A. L. Zydney, "Effect of Ion Binding on Protein Transport Through Ultrafiltration Membranes", Biotech. Bioeng., 63, 298-307 (1999)

  94. Zydney, A. L., "Membrane Systems Do it All", Chemical Processing, 59-62 (2000)

  95. Ho, C-C., and A. L. Zydney, "Measurement of Membrane Pore Interconnectivity", J. Membrane Sci., 170, 101-112 (2000)

  96. Soltys, P. J., J. K. Leypoldt, L. W. Henderson, A. L. Zydney, and N. J. Ofsthun, "Potential of Dual-Skinned High-Flux Membranes to Reduce Backtransport", Kidney International, 58, 818-828 (2000)

  97. Zydney, A. L., "Therapeutic Apheresis and Blood Fractionation", The Biomedical Engineering Handbook, 2nd Edition, II, 132.1-132.15 (2000)

  98. Zydney, A. L., "Membrane Separations: Membrane Bioseparations," in Encyclopedia of Separation Science, Academic Press, Ltd., London, pp. 1748-1755 (2000)

  99. Kuriyel, R., and A. L. Zydney, "Sterile Filtration and Virus Filtration", Methods in Biotechnology, Downstream Protein Processing, ed. By M. Desai, 9, 185-194, Humana Press, Totowa, NJ (2000)

  100. Zydney, A. L., and R. Kuriyel, "Protein Concentration and Buffer Exchange", Methods in Biotechnology, Vol. 9, Downstream Protein Processing, ed. By M. Desai, 35-46 (2000)

  101. Zydney, A. L., and R. Kuriyel, "High-Performance Tangential Flow Filtration for Protein Separations," in Methods in Biotechnology,Downstream Protein Processing, edited by M. Desai, pp. 23-34, Humana Press, Totowa, NJ (2000)

  102. Ho, C-C., and A. L. Zydney, "A Combined Pore Blockage and Cake Filtration Model for Protein Fouling during Microfiltration", J. Colloid Interface Sci., 232, 389- 399 (2000)

  103. Yuan, W., and A. L. Zydney, "Humic Acid Fouling During Ultrafiltration", Env. Sci. Tech., 34, 5043-5050 (2000)

  104. Burns, D.B., and A. L. Zydney, "Buffer Effects on the Zeta Potential of Ultrafiltration Membranes", J. Membrane Sci., 172, 39-48 (2000)

  105. Menon, M. K., and A. L. Zydney, "Determination of Effective Protein Charge by Capillary Electrophoresis: Effects of Charge Regulation in the Analysis of Charge Ladders", Anal. Chem., 72, 5714-5717 (2000)

  106. Ho, C-C., and A. L. Zydney, "Protein Fouling of Asymmetric and Composite Microfiltration Membranes", Ind. Eng. Chem. Res., 40, 1412-1421 (2001)

  107. Zydney, A. L., and R. van Reis, "High Performance Tangential Flow Filtration", Membrane Separations in Biotechnology, 2nd edition, ed. by W.K. Wang, Marcel Dekker, Inc., pp. 277-298 (2001)

  108. Van Reis, R., and A. L. Zydney, "Membrane Separations in Biotechnology", Current Opin. Biotech., 12, 208- 211 (2001)

  109. Menon, M.K., and A. L. Zydney, "Protein Charge Ladders: A New Technique for Studying Electrostatic Interactions in Ultrafiltration Systems", J. Membrane Sci., 181, 179- 184 (2001)

  110. Burns, D.B., and A. L. Zydney, "Contributions to Electrostatic Interactions on Protein Transport in Membrane Systems", AIChE J., 47, 1101-1114 (2001)

  111. Romero, J.R., and A.L. Zydney, "Chiral Separations Using Ultrafiltration with a Stereoselective Binding Agent", Sep. Sci. Tech., 36, 1571-1590 (2001)

  112. Palacio, L., C-C. Ho, and A. L. Zydney, "Application of a Pore Blockage - Cake Filtration Model to Protein Fouling during Microfiltration", Biotech. Bioeng. 79, 260-270 (2002)

  113. Yuan, W., A. Kocic, and A. L. Zydney, "Analysis of Humic Acid Fouling using a Combined Pore Blockage - Cake Filtration Model", J. Membrane Sci., 198, 51-62 (2002)

  114. Romero, J.R., and A. L. Zydney, "Affinity Ultrafiltration: Effect of Ligand Binding on Selectivity and Overall Performance", Biotech. Bioeng., 77, 256-265 (2002)

  115. Strano, M. S., A. L. Zydney, H. Barth, G. Wooler, H. Agarwal, and H. C. Foley, "Ultrafiltration Membrane Synthesis by Nanoscale Templating or Porous Carbon", J. Membrane Sci., 198, 173-186 (2002)

  116. Zydney, A. L., J. S. Bennett, A. Shahid, and K. W. Bauer, "Impact of Undergraduate Research Experience in Engineering," J. Eng. Education, 91 (2), 151 - 157 (2002)

  117. Zydney, A. L., and C-C. Ho, "Scale-Up of Microfiltration Systems: Fouling Phenomena and Vmax Analysis," Desalination, 146, 75 - 81 (2002)

  118. Romero, J. R., and A. L. Zydney, "pH and Salt Effects on Chiral Separations Using Affinity Ultrafiltration," Desalination, 148, 159 - 164 (2002)

  119. Romero, J. R., and A. L. Zydney, "Staging of Affinity Ultrafiltration Processes for Chiral Separations," J. Membrane Sci., 209, 107 - 119 (2002)

  120. Zydney, A. L., J. S. Bennett, A. Shahid, and K. W. Bauer, "Faculty Perspectives on the Undergraduate Research Experience in Science and Engineering," J. Eng. Education, 91 (3): 291 - 297 (2002)

  121. Ho, C-C., and A. L. Zydney, "Transmembrane Pressure Profiles during Constant Flux Microfiltration of Bovine Serum Albumin," J. Membrane Sci., 209, 363 - 377 (2002)

  122. Zydney, A. L., "Analysis of Membrane Processes in the Introduction to Chemical Engineering Course," Chem. Eng. Education, 36(1), 33 - 37 (2003)

  123. Cheang, B., and A. L. Zydney, "Separation of a-Lactalbumin and b-Lactoglobulin using Membrane Ultrafiltration," Biotech. Bioeng., 83(2), 201 - 209 (2003)

  124. Zydney, A. L., and C-C. Ho, "Effect of Membrane Morphology on System Capacity During Normal Flow Microfiltration," Biotech. Bioeng., 83(5), 537 - 543 (2003)

  125. Palacio, L., C. -C. Ho, P. Prádanos, A. Hernández, and A. L. Zydney, "Fouling with Protein Mixtures in Microfiltration: BSA-Lysozyme and BSA-Pepsin," J. Membrane Sci., 222, 41-51 (2003)

  126. Morti, S., J. Shao, and A. L. Zydney, "Importance of Asymmetric Structure in Determining Mass Transport Characteristics of Hollow Fiber Hemodialyzers," J. Membrane Sci., 224, 39 - 49 (2003)

  127. Kim, M-M., and A. L. Zydney, "Effect of Electrostatic, Hydrodynamic, and Brownian Forces on Particle Trajectories and Sieving in Normal Flow Filtration," J. Colloid Interf. Sci., 269: 425 - 431 (2004)

  128. Ebersold, M.F., and A. L. Zydney, "Use of Protein Charge Ladders to Study Electrostatic Interactions During Protein Ultrafiltration," Biotech. Bioeng., 85(2): 166 - 176 (2004)

  129. Cheang, B., and A. L. Zydney, "A Two-Stage Ultrafiltration Process for Fractionation of Whey Protein Isolate," J. Membrane Sci., 231: 159-167 (2004)

  130. Ebersold, M.F., and A. L. Zydney, "Separation of Protein Charge Variants by Ultrafiltration," Biotech. Prog., 20: 543 - 549 (2004)

  131. Shao, J.H., and A. L. Zydney, "Effect of Bleach Reprocessing Upon the Clearance Characteristics and Surface Charge of Polysulfone Hemodialyzers," American Soc. Artificial Internal Organs., 50, 246 - 252 (2004)

  132. Shao, J.H., and A. L. Zydney, "Retention of Small Charged Impurities during Ultrafiltration," Biotech. Bioeng., 87(1): 7 - 13 (2004)

  133. Chandler, M.C., and A. L. Zydney, "High Throughput Screening for Membrane Process Development," J. Membrane Sci., 237, 181 - 188 (2004)

  134. Shao, J.H., and A. L. Zydney, "Optimization of Ultrafiltration / Diafiltration Processes for Partially Bound Impurities," Biotech. Bioeng., 87(3): 286 - 292 (2004)

  135. Ebersold, M.F., and A. L. Zydney, "The effect of membrane properties on the separation of protein charge variants using ultrafiltration," J. Membrane Sci., 243: 379 - 388 (2004)

  136. Wolff, S.H., and A. L. Zydney, "Effect of bleach on the transport characteristics of polysulfone hemodialyzers," J. Membrane Sci., 243: 389 - 399 (2004)

  137. Wolff, S.H., and A. L. Zydney, "Effect of peracetic acid reprocessing on the transport characteristics of polysulfone hemodialyzers," Artificial Organs, 29: 166 - 173 (2005)

  138. Mehta, A., and A. L. Zydney, "Permeability and selectivity analysis for ultrafiltration membranes," J. Membrane Sci., 249: 245 - 249 (2005)

  139. Bohonak, D. and A. L. Zydney, "Compaction and permeability effects with virus filtration membranes," J. Membrane Sci., 254: 71 - 79 (2005)

  140. Rao, S., and A. L. Zydney, "Controlling protein transport in ultrafiltration using small charged ligands," Biotech. Bioeng., 91(6): 733 - 742 (2005)

  141. Chandler, M.C., and A. L. Zydney, "Clarification of yeast cell suspensions by depth filtration," Biotech. Prog., 21, 1552 - 1557 (2005)

  142. Shaffer, J.F., and A. L. Zydney "Phosphate clearance for bleach reprocessed polysulfone dialyzers: Effects of electrostatic interactions," American Soc. Artificial Internal Organs., 51, 748 - 753 (2005)

  143. Mehta, A., and A. L. Zydney, "Effect of Membrane Charge on Flow an Protein Transport during Ultrafiltration," Biotech. Prog., 22: 484 - 492 (2006)

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